0 points
Time management is very much important in IIT JAM. The eduncle test series for IIT JAM Mathematical Statistics helped me a lot in this portion. I am very thankful to the test series I bought from eduncle.
Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
- CSIR NET
- Life Sciences
A Lod score of 3 represent a Recombination Frequency (RF) that is
Choose Your Answer:
0 Attempts
Submit Now
- 0 Likes
- 1 Comments
- 0 Shares
-
![comment-profile-img]()
>
Do You Want Better RANK in Your Exam?
Start Your Preparations with Eduncle’s FREE Study Material
- Updated Syllabus, Paper Pattern & Full Exam Details
- Sample Theory of Most Important Topic
- Model Test Paper with Detailed Solutions
- Last 5 Years Question Papers & Answers
Sign Up to Download FREE Study Material Worth Rs. 500/-
Eduncle Best Answer
LOD score is actually an acronym for "log of the odds," LOD. LOD score actually refers to a numerical result when estimating whether two genes, or a gene and a disease, are linked to one another. LOD scores are most often used to describe the data one gets out of family studies where you are looking at large families and an inheritance of traits or diseases within the families. So you can have the gene of interest unlinked to your disease and have a very low LOD score. In a family where the gene and a particular disease are segregating or being inherited together the odds of those being linked can actually be quite great and that would be a large LOD score. For example, in a pedigree to prove that a gene is linked to a condition we usually say that the LOD score has to be above 3. 3 is translated roughly into about 1,000-to-one odds that this gene really is linked to this disease as opposed to the alternative hypothesis which is unlinked. So therefore the higher the LOD score the more likely the two things you are following, usually a disease and a gene or a marker, actually are truly linked in the family.