Inushaa posted an Question
October 31, 2021 • 12:01 pm 30 points
  • CSIR NET
  • Life Sciences

Can you please say me the summary of it

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  • Priya sarda

    I have written the important aspects of this paper. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells.  Types of cell Totipotent stem cells are able to divide and differentiate into cells of the whole organism.  Pluripotent stem cells (PSCs) form cells of all germ layers but not extraembryonic structures, such as the placenta.  Multipotent stem cells have a narrower spectrum of differentiation than PSCs, but they can specialize in discrete cells of specific cell lineages. Oligopotent stem cells can differentiate into several cell types. Unipotent stem cells are characterized by the narrowest differentiation capabilities and a special property of dividing repeatedly. Mesenchymal stem cells are present in many tissues.  Neural cells give rise to nerve cells and their supporting cells—oligodendrocytes and astrocytes. Haematopoietic stem cells form all kinds of blood cells: red, white, and platelets. Skin stem cells form, for example, keratinocytes, which form a protective layer of skin. Periodontal ligament stem cells (PDLSCs) These cells are used in periodontal ligament or cementum tissue regeneration. Dental pulp stem cell (DPSC) These were the first dental stem cells isolated from the human dental pulp, which were located inside dental pulp . The turning point in stem cell therapy appeared in 2006, when scientists Shinya Yamanaka, together with Kazutoshi Takahashi, discovered that it is possible to reprogram multipotent adult stem cells to the pluripotent state.  The former discovery was about scientist John Gurdon successfully cloning frogs by transferring a nucleus from a frog’s somatic cells into an oocyte.  After several decades of experiments, stem cell therapy is becoming a magnificent game changer for medicine.

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