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December 10, 2021 10:56 pmpts 5 pts
CSIR NEI DEC C) 334. Histidine is the active site residue in a large number of enzyme because a) The pKa of the imidazole moiety in the histidine is 6.5 b) It forms salt bridges with lysine residue in the substrate c) It forms hydrogen bonds with the residues in the substrate d) It is a good buffering agent at the physiological pH JIISc Bangalore
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  • Krishan k jakhad thankyou
    D. good buffer and pKa is 6.8 close to physiological pH. side chain immidazole can perform catalysis, when protonated acts as general acid by donating it's proton to the substrate.
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