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Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
Anup Padwal
Specification: First stage of commitment, it is reversible if we change cell position cell fate changes. Types of Specification: I. Autonomous specification: e.g. Invertebrate, signal present in cytosol, specification and determination at early 8 cell stage, Potency=fate. II. Conditional specification: eg. Vertebrate and some invertebrate, signal from neighbouring cell by by direct or indirect interaction, at late blastula and early gastrula, potency>fate. III. Syncytial specification: eg. Insects, gradient of morphogen (acts as transcription factor)in single cell, specification and determination at cellular blastoderm.