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Eduncle Best Answer
The bases can exist in two distinct orientations about the N-glycosidic bond. These conformations are identified as, syn and anti. It is the anti conformation that predominates in naturally occurring nucleotides. i.e. in both B and A forms of DNA duplexes. There is only one known case where a purine adopts a syn conformation. The unusual form is to find in an even more unusual structure namely left handed Z-DNA.