0 points
Time management is very much important in IIT JAM. The eduncle test series for IIT JAM Mathematical Statistics helped me a lot in this portion. I am very thankful to the test series I bought from eduncle.
Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
- CSIR NET
- Life Sciences
Following statements have been made about removal of supercoiling produced by DNA unwinding at the replication fork :
Following statements have been made about removal of supercoiling produced by DNA unwinding at the replication fork : (A) Accumulation of supercoils is the result of DNA helicase activity during unwinding of DNA (B) Problem of DNA supercoiling is valid only for circular chromosomes of bacteria and not for the linear chromosomes (C) Supercoiling of DNA is removed by topoisomerases by breaking either one or both strands of DNA on the unreplicated DNA in front of replication fork. (D) Both topoisomerase I and topoisomerase II can remove positive supercoiling during replication Which one of the following options has all correct statements:
Choose Your Answer:
0 Attempts
Submit Now
- 0 Likes
- 1 Comments
- 0 Shares
-
![comment-profile-img]()
>
Do You Want Better RANK in Your Exam?
Start Your Preparations with Eduncle’s FREE Study Material
- Updated Syllabus, Paper Pattern & Full Exam Details
- Sample Theory of Most Important Topic
- Model Test Paper with Detailed Solutions
- Last 5 Years Question Papers & Answers
Sign Up to Download FREE Study Material Worth Rs. 500/-
Eduncle Best Answer
DNA supercoils are generated during replication because of the DNA helicase eliminating the base pair between the two strands. Supercoiling occurs in both circular and linear DNA. Topoisomerases are used to resolves the supercoils. Type I topoisomerases cleave one strand of DNA and Type II topoisomerases cleave both the strands to resolve the supercoils. Both Type I and II can resolve positive supercoils.