Time management is very much important in IIT JAM. The eduncle test series for IIT JAM Mathematical Statistics helped me a lot in this portion. I am very thankful to the test series I bought from eduncle.
Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
Priya sarda
The simple rule of thumb for solubility is that “like dissolves like”. So polar and charged substances are more likely to dissolve in polar or charged solvents; non-polar substances are more likely to be able to dissolve in non-polar solvents. The cell membrane is a lipid bilayer, a fat-based barrier that separates an aqueous environment outside the cell from the aqueous cytoplasm within it. Substances that dissolve well in the lipid bilayer are likely to be similarly non-polar and this is why a molecule like benzene can diffuse across this barrier quite easily. It’s also the reason why membrane-spanning proteins have regions full of amino acids with non-polar side-chains corresponding to the part of the protein in contact with the hydrophobic lipid layer. Any part of a membrane protein that pokes out into the aqueous medium on either side is conversely rich in amino acids with charged and polar side-chains.