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In the glomerular capillary (GC), fluid moves into Bowman's capsule through its almost entire length. But in the muscle capillary (MC),
In the glomerular capillary (GC), fluid moves into Bowman's capsule through its almost entire length. But in the muscle capillary (MC), fluid moves into interstitial space at its arteriolar end. The difference between these two capillaries is explained in the following proposed statements : (a) Afferent and efferent arterioles are present on the two ends of GC, but in MC, arteriole and venule are present on two ends. (b) The hydrostatic pressure in GC is higher than that in MC. (c) The efferent arteriole in GC has a relatively low resistance, but venules in MC has a high resistance. (d) The difference of hydrostatic pressure between two ends of GC is relatively more but it is negligible in MC. (e) The difference of oncotic pressure between two ends of MC is negligible but it is relatively more in GC. (f) The net filtration pressure falls to zero at the efferent end of GC but it is 9 mm Hg inward at the venular end of MC. Which of the above statements are INCORRECT ?
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Eduncle Best Answer
Glomerulus supplied by afferent arteriole from arcuate arteries (branched from renal artery from aorta). The afferent arteriole is of much higher pressure than the efferent arteriole, creating a pressure gradient which drives ultrafiltration. The special arrangement of the glomerular circulation with arterioles before and after the capillary bed leads to a unique set of capillary fluid dynamics. Resistance to blood flow is applied downstream of the glomerular capillaries by the efferent arterioles varying their diameter. This results in a relatively higher hydrostatic pressure which is maintained along the whole length of the glomerular capillaries thereby favouring the filtration process. Since statement C mentions efferent arteriole in GC offers less resistance, this statement is wrong. Glomerular hydrostatic pressure is more due to short, wide, less resistance afferent arteriole which is essential for glomerular filtration process.