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Aniket Ganvir posted an Question
February 14, 2022 • 20:33 pm 30 points
  • CSIR NET
  • Life Sciences

Meselson and sthal experiment

i wanna need of whole topic of Meselson and Franklin W sthal experiment in deep . Query ; 1 ) if DNA replication occurs conservative where will get the bands in centrifugal tube ? 2) same query happened in semiconservative and Dispersive .

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  • Priya sarda best-answer

    The Meselson–Stahl experiment is an experiment by Matthew Meselson and Franklin Stahl in 1958 which supported Watson and Crick's hypothesis that DNA replication was semiconservative. Meselson & Stahl reasoned that these experiments showed that DNA replication was semi-conservative: the DNA strands separate and each makes a copy of itself, so that each daughter molecule comprises one "old" and one "new" strand. CsCl density gradient centrifugation Process used by Meselson and Stahl for studying semiconservative replication of DNA was CsCl density gradient centrifugation. How did Meselson and Stahl distinguish between semiconservative and dispersive replication in their experiment? After one round of replication, both heavy and light DNA single strands were present in alkaline gradients. ... Replication initiates from a single origin, creating a single replication bubble in the plasmid.

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    Priyaji yes i knew it about whole but i wanna whole experiment and their conclusion and results this is my actual problem

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    can you help me ?

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    see if this helps

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