The extracellular matrix (ECM) is a complex combination of secreted proteins that is involved in holding cells and tissues together. The components of ECM form a network by binding to each other and communicate with cells by binding to adhesion receptors on the cell surface. ECM comprises mainly two classes of macromolecules, proteoglycans and very high molecular weight large proteins.
Which one of the following statements regarding ECM constituents is INCORRECT ?

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AProteoglycans are a subset of secreted or cell surface-attached glycoproteins containing covalently linked specialized polysaccharide chains called glycosaminoglycans (GAGs).

BGAGs are long branched polymers of specific repeating disaccharides of sialic acid and glucose or galactose.

CMajor types of GAGs present in ECM are heparan sulphate, chondroitin sulphate, dermatan sulphate, keratan sulphate and hyaluronan.

DMajor types of large proteins present in ECM are collagen, laminin, elastin and fibronectin.

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Eduncle Best Answer
Glycosaminoglycans (GAGs) are large linear (UNBRANCHED) (hence statement 2 is incorrect) polysaccharides constructed of repeating disaccharide units with the primary configurati...
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