Nayana posted an Question
July 02, 2021 • 12:24 pm 30 points
  • CSIR NET
  • Life Sciences

The first enzyme in a metabolic pathway o sets the rate (i.e.. is a pacemaker) for that pathway ohas a negative gibbs free energy change ois often feedback inhi

The first enzyme in a metabolic pathway O sets the rate (i.e.. is a pacemaker) for that pathway Ohas a negative Gibbs free energy change Ois often feedback inhibited O All of the above O None of the above

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    Krishan k jakhad best-answer

    D. all the above see diagram for illustration. actually first enzyme. phosphofructokinase step The phosphofructokinase step is rate-limiting step of glycolysis. High AMP/ADP levels are activators of this enzyme, while high ATP levels are inhibitory (energy charge). product, fructose-2,6-bisphosphate activates phosphofructokinase-1, the rate limiting step in glycolysis. In the first reaction of glycolysis, the gamma-phosphoryl group of an ATP molecule is transferred to the oxygen at the C-6 of glucose. This produces glucose-6-phosphate and ADP. Hexokinase is the enzyme that catalyzes this phosphoryl group transfer.

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