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Bishal Paul posted an Question

April 09, 2021 • 02:53 am

30 points

CSIR NET
Life Sciences

Vesicular trafficking: secretory and endocytotic pathway

Please provide full notes on this topic "Vesicular trafficking: Secretory and endocytic pathway"

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Varsha

nice answer
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Krishan k jakhad

Exocytosis is a process allowing secretion of proteins, hormones, neurotransmitters, plasma membrane glycoproteins and receptors, and antigen presentation during the immune system reaction. There are two mediated pathways for exocytosis: calcium-mediated, in neurons and a non-calcium mediated pathways, which is commonly used by cells to release exocytic vesicles. Exocytosis is a four steps process: approach to plasma membrane, vesicle tethering, vesicle docking and vesicle fusion. Vesicles approach the plasma membrane by using motor proteins, such as kinesin or dynein, advancing on a microtubule track. When the vesicle is near the membrane it will loosely attach via the binding of Rab-GTP on the vesicle surface to Rab effector protein at the target membrane surface. Vesicles docking and fusion to the membrane is ensured by SNARE proteins. There are mainly two types of SNARE proteins: vesicle v-SNARE: synaptobrevin and target t-SNARE: syntaxin, SNAP25. The binding of v-SNARE with t-SNARE triggers the fusion of the membrane vesicles to the plasma membrane.
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Dear sir please explain secretory pathway also
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okay Bishal see exocytosis means something is secreted outside the cell so also termed secretory pathway already explained
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if you need anything related to endocytosis I may help u
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