Mohanchaitanya Reddy posted an Question
June 16, 2020 • 22:36 pm 30 points
  • IIT JAM
  • Biotechnology (BT)

23. if host cells infected with a pathogenic rna vinus were grown

please explain with mechanism how actually happens..

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  • Abhijeet Gaurav Best Answer

    Answer is (D) Both options A & C are correct. As here the Pathogenic RNA virus infect the host cell so they Will take over the machinery of host & take them in use for making proteins necessary for their duplication & multiplication of new viruses. As the proteins obtained Will help in their Replication of their genetic material that is RNA here. Now taking refernce from Hershey- Chase Experiment as the provided media contains Radiolabelled 14C dUTP so the newly synthesised RNA strand formed of Pathogenic RNA virus Will contain the 14C that is Radiolabelled. Now the host cell Will undergo RNA formation so it Will also utilise the media containing 14C Radiolabelled dUTP in it. So it's newly synthesised RNA strand Will be Radiolabelled thus. So above explaination just justifies both A & C options in the answer.

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    but the answer is given as option B... i thought Same as you.. but the answer is given wrong .. it is in HCU 2019 Msc biochemistry paper Q)23

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    Regarding this question I clarified through many of my colleagues & Professors even. But no one seem to have a Logic fir the options B. Everybody said answer is D. But if I get something I Will get back to you soon.

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