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Arindam Paul posted an Question
June 02, 2021 • 18:14 pm
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30 points
30 points
- IIT JAM
- Biotechnology (BT)
34. the blood clotting factors which cause coagulation of blood are mostly serine proteases and they exist in circulatory system as inactive enzyme precursors c
34. The blood clotting factors which cause coagulation of blood are mostly serine proteases and they exist in circulatory system as inactive enzyme precursors called as A. Halogens B. Zymogens C. Glucogens D. Haemogens
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Abhijeet Gaurav![best-answer]()
correct answer is option (B). The coagulation cascade of secondary hemostasis has two initial pathways which lead to fibrin formation. These are the contact activation pathway (also known as the intrinsic pathway), and the tissue factor pathway (also known as the extrinsic pathway) which both lead to the same fundamental reactions that produce fibrin. But the primary pathway is the tissue factor (extrinsic) pathway. The pathways are a series of reactions, in which a zymogen (inactive enzyme precursor) of a serine protease and its glycoprotein co-factor are activated to become active components that then catalyze the next reaction in the cascade, ultimately resulting in cross-linked fibrin. Coagulation factors are generally indicated by Roman numerals, with a lowercase a appended to indicate an active form.