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Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
- IIT JAM
- Chemistry (CY)
50. fe2-porphyrins fail to exhibit reversible oxygen transport and canno differentiate co from o2, however, these problems are not there wit haemoglobin because
50. Fe2-porphyrins fail to exhibit reversible Oxygen transport and canno differentiate CO from O2, however, these problems are not there wit haemoglobin because (A Fe-CO bond strength is lower in the caSe ul iClliuglubin as COipared u Fe-porphyrins (B) Fe4 -porphyrin undergo peroxo, (Fe-0-0--Fc) complex formation whict 1s prevcnted in the case of haemoglobin (C) Fe-CO is linear while Fe-O, is bent which is recognised in haemoglobin (DI the interlinked 4-units in haem0gooin Overcomes these problems e t COoperativity (1) (A) and (B) (2 (B) and (C) (3) (C) and (D) (4) (D) and (A) 10
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Dinesh khalmaniya 1 Best Answer
option 2 B and C are correct Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion. The protein is produced by almost all living organisms, including archaea, bacteria, algae, higher plants, and animals. In humans, it acts as a buffer against iron deficiency and iron overload.[ Ferritin is found in most tissues as a cytosolic protein, but small amounts are secreted into the serum where it functions as an iron carrier. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia.
sir this explanation does not match with th options
How porphyrin undergo peroxo complex ??
it's theoretical question, so you should remember theory
iron porphyrin form per oxo complex
ok sir but option D b toh correct explanation h na ?
Toh sir option (3) shi ni ho skta?
wait app is working slowly
sir ?
C is also correct Hb-CO complex is linear while Hb-O2 complex is bent
got it?
The interlinked 4 units to hameoglobin overcomes these problems due to cooperativity ye wala option shi h ki ni ??
incorrect. because hemoglobin tetramer unit hota he or each hemoglobin four O2 ko bind kr skta he, same as four hi CO ko bind kr skta he.. isse bonding pr koi effect nhi pdega