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Ashutosh posted an Question
September 15, 2020 • 18:46 pm 30 points
  • IIT JAM
  • Biotechnology (BT)

An rna-dna hybrid of gene sequence with its transcript contains some loops. this indicates that (a) the gene has undergone a frameahift mutation (b) the mrna is

An RNA-DNA hybrid of gene sequence with its transcript contains some loops. This indicates that (a) the gene has undergone a frameahift mutation (b) the mRNA is polycistronic (c) the mRNA is edited (d) the gene contains introns

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    Narayan singh Best Answer

    In the laboratory, the loops may also be created by the hybridization of mature mRNA with double-stranded DNA under conditions favoring the formation of a DNA-RNA hybrid; in this case, the intron regions (which have been spliced out of the mRNA) form single-stranded loops, as they cannot hybridize with complementary sequence in the mRNA. so ans is 4th due to non coding region introns...

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    Anup Padwal best-answer

    Option D due to introns in gene. In the laboratory, R-loops may also be created hybridization of mature mRNA with double-stranded DNA under conditions favoring the formation of a DNA-RNA hybrid; in this case, the intron  regions (which have been spliced  out of the mRNA) form single-stranded loops, as they cannot hybridize with complementary sequence in the mRNA.

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