Simun Mishra posted an Question
July 27, 2020 β€’ 19:32 pm 30 points
  • IIT JAM
  • Chemistry (CY)

Can u explain me this 2 acidcatalyzed and base catalyzed reaction ?

2 Answer(s) Answer Now
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    Dinesh khalmaniya 1

    but in this case also wolff rearrangement type rearrangement takes place.

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  • Suman Kumar Best Answer

    Mechanism is given. For hydroxamate ester we use base as catalyst

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    For hydroxamic acid H+ is used as catalyst.

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    Now you tell me in which step you are facing problem

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    As in both case substrate is different so we use catalyst accordingly

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    Thank you 😊 Simun

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    You are always welcome dear 😘

  • comment-profile-img>
    Dinesh khalmaniya 1 best-answer

    yes

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    in which step do you have doubt?

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    sir why here 2 mechanism of the reaction

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    here we are use two media 1) acid and 2) base so in both the media reaction will be different

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    in the acid media reactant is H+ so it attracks on OH group

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    but sir in fast and second case the reactant are different na

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    yes if we are using ester of hydroxamic acid the we have to take base

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    if we are using hydroxamic acid the take acid

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    sir pls tell me which compounds will give this rearrangment

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    keto nitrene and keto carbene both gives rearrangement

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    both give same type of rearrangement like wolff rearrangement

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    I m fully confused about this Lossen rearrangement sir

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    okay the start from starting

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    what is your doubt. where are you confused??

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    spacificly which compounds give reaction then how it will react the mechanism ...all of this

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    sir can u explain me from starting ...

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    hydroxamic acid gives losses product in acidic medium. if we want to proceed this reaction in base media the we have to convert hydroxamic acid into hydroxamic ester

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    now hydroxamic acid also give lossen rearrangement in base media

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    hydroxamic ester give reaction in base medium na ?

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    yes yes

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    only hydroxamic acid and hydroxamic ester gives Lossen rearrangement na sir ?

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    sir pls send me simply in which cases Wolff rearangments take place

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    yee

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    wait..

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    ok sir

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    mainly in this case

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    check now, how simple this reaction is

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    yes sir now I got it

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    πŸ˜ŠπŸ˜ŠπŸ‘

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    tqqq sir πŸ™πŸ™

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