Nisarg posted an Question
April 20, 2021 • 22:16 pm 30 points
  • IIT JAM
  • Biotechnology (BT)

Macrolides and chloromphenicol both can block action of peptidyle transferase but macrolides can also inhibit the translocation right?

macrolides and chloromphenicol both can block action of peptidyle transferase but macrolides can also inhibit the translocation right?

1 Answer(s) Answer Now
  • 0 Likes
  • 1 Comments
  • 0 Shares
  • comment-profile-img>
    Krishan k jakhad best-answer

    Yes true..... Macrolides, lincosamides, tetracyclines and chloramphenicol are structurally unrelated antibiotics which share protein synthesis inhibition as their common mechanism of action. The macrolide antibiotics contain a large macrocyclic lactone ring to which one or more deoxysugar may be attached. These antibiotics inhibit bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome and preventing translocation of peptidyl-tRNA

    cropped4614601090283866109.jpg
whatsapp-btn

Do You Want Better RANK in Your Exam?

Start Your Preparations with Eduncle’s FREE Study Material

  • Updated Syllabus, Paper Pattern & Full Exam Details
  • Sample Theory of Most Important Topic
  • Model Test Paper with Detailed Solutions
  • Last 5 Years Question Papers & Answers