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Shweta Thakur posted an Question

February 19, 2021 • 19:24 pm

30 points

IIT JAM
Chemistry (CY)

Please send the mechanism for the formation of imine from aldehyde and ketones

please send the mechanism for formation of email from for aldehyde and

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Priyanshu kumar

Mechanism
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Amol ashok pawar Best Answer

This is the mechanism
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sir
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in acidic medium there is always first attack of hydrogen on oxygen
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right n
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yes that is the protonation step. it makes attack easier
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sir but in some sites there is attack of nucleophile first
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..
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yes it is correct
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but sir first step is attack of h on carbon
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that is just an alternative way, the mechanism you posted is still relevant, as attach of nitrogen lone pair on carbonyl.
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the protonation step you are talking about is just other way to get product. both are correct.
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ok
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and sir I am getting confused in acidic and basic medium
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it's very easy, in acidic mediums the protonation of oxygen occurs first and then attack of nitrogen lone pair, and in basic medium direct attack of nitrogen lone pair takes place.
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it means that attack of amine to carbonyl compound should be occur be acidic medium as given in my book and the first step shoul be attack of h on oxygen
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be ~in**
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yes
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why reaction of weak nucleophile occurs under acidic condition and those of strong nucleophile occur under basic condition why
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?
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these conditions are followed to makes the reaction more feasible to get product. activation energy is lowered so as to get maximum amount of product in best possible condition
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