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Arindam Paul posted an Question
September 02, 2020 • 11:52 am 30 points
  • IIT JAM
  • Biotechnology (BT)

Proinsulin is an 84 residue polypeptide with six cysteines. how many different disulfide combinations are possible?

Proinsulin is an 84 residue polypeptide with six cysteines. How many different disulfide combinations are possible?

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    Aarif sir Best Answer

    In the first case 5 bonds are possible. In the second case only 4 new possibilities are there since the possibility of the first residue and the second residue forming a bond was already considered in the first case. Like wise in the third case 5 new possibilities are there because the bond between the first-second residue and the second-third residue was already counted in the first case. Do the same thing for the rest of the cases and you get the total possibilities as 5+4+3+2+1= 15 so dear student this picture for 8 bond ok can underu by this...

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