Karnan posted an Question
November 01, 2020 • 13:47 pm 30 points
  • IIT JAM
  • Chemistry (CY)

Reactive intermediate formed in the following reaction is: nh2 52 nh2 co + naoh a) carbene b) lsocyanate c) nitrene d) carbanion

Reactive intermediate formed in the following reaction is: NH2 52 NH2 CO + NaOH a) Carbene b) lsocyanate c) Nitrene d) Carbanion

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    Priyanshu kumar best-answer

    Option B isocyanate intermediate The reaction of bromine with sodium hydroxide leads to the formation of sodium hypobromite (NaOBr) which in turn transforms the primary amide into an isocyanate intermediate.

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    please ask aswin if any doubt

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    Dinesh khalmaniya 1 best-answer

    option B Explainion- When an amide is treated with bromine in an aqueous or ethanolic solution of sodium hydroxide, degradation of amide takes place leading to the formation of primary amine. This reaction involving degradation of amide and is popularly known as Hoffmann bromamide degradation reaction. The primary amine thus formed contains one carbon less than the number of carbon atoms in that amide. RCONH2 +Br2 + 4NaOH → R-NH2 + Na2CO3 + 2NaBr + 2H2O

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