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Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
Dinesh khalmaniya 1
You should consider several factors: Solvent (may or may not deactivate nucleophile) Sterics (of substrate or nucleophile; more sterics = less second-order reactions, and vice versa) Reagent pKas (high pKas allow elimination as a possible side mechanism) Temperature (high temperatures favor elimination) Leaving group propensity (great leaving groups favor first-order reactions, such as E1 or SN1) This table summarizes what we'll look at.