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Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
- IIT JAM
- Biotechnology (BT)
Tears antibecterials (phospholipase a2)......
Tears Antibecterials (phospholipase A2)...... .. plzz explain mee....I am fully confused..... wt is the connection between tears antibacterial and phospholipase A2
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Abhijeet Gaurav Best Answer
The physiological function of secreted phospholipase A2 (sPLA2) group IIA (sPLA2-IIA) is defense against bacterial infection through hydrolytic degradation of bacterial membrane phospholipids. In fact, sPLA2-IIA effectively kills Gram-positive bacteria and to a lesser extent Gram-negative bacteria and is considered a major component of the eye's innate immune defense system. The antibacterial properties of sPLA2 have been demonstrated in rabbit and human tears.
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