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Arindam Paul posted an Question
February 10, 2021 • 16:33 pm 30 points
  • IIT JAM
  • Biotechnology (BT)

The binding of oxygen to haemoglobin is affected by (a) hemoglobin concentration (b) partial pressure of oxygen (c) bicarbonate concentration (d) 2, 3-biphospho

The binding of oxygen to haemoglobin is affected by (A) hemoglobin concentration (B) partial pressure of oxygen (C) bicarbonate concentration (D) 2, 3-biphosphoglyceric acid

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    Yogita Basnal best-answer

    Option D: 2,3 bisphosphoglyceric acid is right answer. Explaination: 2,3-bisphosphoglyceric acid is formed from 3-phosphoglyceric acid which is the product of glycolysis. When concentration of 2,3-bisphosphoglyceric acid increases it tends to bind the beta chain of deoxy-haemoglobin which causes oxy- hemoglobin dissociation curve to shift in the rightward direction. A shift of Hb - O2 dissociation curve into rightward direction results into unloading of oxygen into the body tissues. This is how oxygen our body tissues get oxygen.

  • Mehrunnisa

    on increasing partial pressure of oxygen hb saturation level inc for binding oxygen

  • Mehrunnisa

    answer is d because BPG is intermediate of glycolysis pathway which may occur in RBC so it will bind in center of polypeptide of hb so binding of Oxygen affinity decreases

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    ans given partial pressure of oxygen

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