Nisarg Asked a Question
April 20, 2021 4:49 pmpts 30 pts
There is line which says that the beta-lactamase resistant penicillins tend to be comparatively lipophilic molecules that do not go inside the gram -ve bacteria. But gram -ve bacteria have bilayer of lipid which is hydrophobic(lipophilic) in nature so it will definitely allow the movement of lipophilic molecules over lipophobic molecules So how this lipophilic penicillins are not able to go through gram -ve bacteria?
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  • Krishan kumar jakhad Best Answer
    3 generations ...Since the introduction of penicillin, β-lactam antibiotics ..BLAs have been the antimicrobial agents of choice. Unfortunately, the efficacy of these life-saving an...
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    Nisarg
    sir this all i know but why don't these lipophlic antimicrobials go through the membrane of gram-ve bacteria even the membrane ia lipophlic?
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