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Arindam Paul posted an MCQ
May 21, 2021 • 14:22 pm 30 points
  • IIT JAM
  • Biotechnology (BT)

What are the deamination product s of cytosine and 5-met hyl cytosine, respectively?

What are t he deamination product s of cyt osine and 5-met hyl cyt osine, respectively

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    Dinesh khalmaniya 1 Best Answer

    While spontaneous deamination of cytosine forms uracil, which is recognized and removed by DNA repair enzymes, deamination of 5-methylcytosine forms thymine. This conversion of a DNA base from cytosine (C) to thymine (T) can result in a transition mutation.

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    Dinesh khalmaniya 1 best-answer

    Deamination of cytosine, adenine, guanine, and 5-methylcytosine forms uracil, hypoxanthine, xanthine, and thymine, respectively. DNA bases can also undergo “spontaneous” hydrolytic deamination (2).

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