What does translesion of dna synthesis means ?

Translesion DNA synthesis (TLS) isthe process by which cells copy DNAcontaining unrepaired damage that blocks progression of the replicationfork. The DNA polymerases that catalyze ...

you can understand this concept in SOS repair mechanism. which is activated when extensive DNA damage. Due to Thiamine-Thiamine dimer which results from UV radiation Polymerase l...