Shweta Thakur posted an Question
July 21, 2021 • 19:24 pm 30 points
  • IIT JAM
  • Chemistry (CY)

What is the use of copper salt in a grignard reagent

what is the use of copper salt in a Grignard reagent

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    Krishna parmar best-answer

    Since the discovery that copper(I) halides catalyze the conjugate addition of Grignard reagents in 1941, organocopper reagents have emerged as weakly basic, nucleophilic reagents for substitution and addition reactions. ... Organocopper complexes (RCu) are produced when a copper(I) halide and organolithium are combined.

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    Dinesh khalmaniya 1 Best Answer

    An organocopper can be made by transmetallating a grignard reagent. This also acts as a nucleophilillic carbanion: Copper is less electropositive, so it produces a less-charged (or "softer") carbanion. And we know soft nucleophiles are a good way to encourage conjugate addition instead of direct attack. Example:

    conjugate addition of organocopper.png
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    sir I only get that it's made grignard reagent a soft nucleophile

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    so that grignard reagent will attack on less polarizes site

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    here due to Cu+ ion nature of RMgX changed to soft so it will give micheal addition. in the question if you see RMgX/CUX the Michele addition product is formed. if only RMgX is given the direct addition

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