Shweta Thakur posted an Question
June 26, 2021 • 18:06 pm 30 points
  • IIT JAM
  • Chemistry (CY)

What this 1ah and 2a c means here vatives la-h and glycine alkyl esters 2a-e are shown to undergo a novel cascade mination- hetcrocylization

Abstract .5-Disubstitued indole-2-carboxaldehyde derivatives la-h and glycine alkyl esters 2a-e are shown to undergo a novel cascade mination- hetcrocylization in the presence ot the organic base DIPEA tO provide I-indoly-5,),8-substitutcd y-carbolines Saa-ea in OOd yiclds. 1ne Y-carbncs arc tnuorescent and cxnibit ancancer ctnvcs against cetvcal, lung. Deast, SKin, and kancy cancer cus.

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