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Which of the following is the corrcct order of reactivity 1owards a nucleophile? (a) acid anhydride> amide > estcr (b) acid anhydride esteramide (c) amide 2este
Which of the following is the corrcct order of reactivity 1owards a nucleophile? (A) acid anhydride> amide > estcr (B) acid anhydride esteramide (C) amide 2ester 2 acid anhydridc (D amide anhydride ester
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Priyanshu kumar![best-answer]()
option B Acid anahydride>ester>amide Explanation:- Carbon in anhydride is more partially positively charges as compared to in ester. This is because of cross conjugation of the Oxygen atom. This allows more nucleophiles to attack that carbon. Amides are less reactive than are esters due to the fact that nitrogen is more willing to donate its electrons than is oxygen.