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Nilanjan Bhowmick AIR 3, CSIR NET (Earth Science)
Gurmeet Singh posted an Question
August 29, 2020 • 03:59 am
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30 points
30 points
- IIT JAM
- Geology (GG)
Which option is correctly representing replication of dna.
which option is correctly representing replication of DNA.
2 Answer(s)
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Sajan sarthak![best-answer]()
Second figure is the answer The replication fork is a structure that forms within the long helical DNA during DNA replication. It is created by helicases, which break the hydrogen bonds holding the two DNA strands together in the helix. The resulting structure has two branching "prongs", each one made up of a single strand of DNA. These two strands serve as the template for the leading and lagging strands, which will be created as DNA polymerase matches complementary nucleotides to the templates; the templates may be properly referred to as the leading strand template and the lagging strand template. DNA is read by DNA polymerase in the 3′ to 5′ direction, meaning the nascent strand is synthesized in the 5' to 3' direction. Since the leading and lagging strand templates are oriented in opposite directions at the replication fork, a major issue is how to achieve synthesis of nascent (new) lagging strand DNA, whose direction of synthesis is opposite to the direction of the growing replication fork.