Shweta Thakur posted an Question
November 12, 2020 • 04:39 am 30 points
  • IIT JAM
  • Chemistry (CY)

White tosyl chloride is very good leaving group

white acyl chloride is very good leaving grohhup high quality of life sciences

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    Dinesh khalmaniya 1 best-answer

    Chlorides, bromides, and tosylate / mesylate groups are excellent leaving groups in nucleophilic substitution reactions, due to resonance delocalization of the developing negative charge on the leaving oxygen.

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    Priyanshu kumar Best Answer

    An examination of the anion formed following the departure of the tosylate group from the compound shows that it is resonance stabilized and the negative charge is spread out among three electronegative oxygen atoms. This is a most stabilizing effect and this is what makes the tosylate group such a good leaving group.

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