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Arindam Paul posted an Question
August 26, 2020 • 22:19 pm
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30 points
30 points
- IIT JAM
- Biotechnology (BT)
Why the antiparallel β sheet is more stable than parallel β sheet?
Why the Antiparallel β sheet is more stable than parallel β sheet?
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Narayan singh Best Answer
Antiparallel ß sheets are slightly more stable than parallel ß sheets because the hydrogen bonding pattern is more optimal. The parallel arrangement is less stable because the geometry of the individual amino acid molecules forces the hydrogen bonds to occur at an angle, making them longer and thus weaker.
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Abhijeet Gaurav
Parallel beta sheets are less stable than anti-parallel beta sheets, because the geometry of the individual amino acid molecules forces the inter chain hydrogen bonds in parallel beta-pleated sheets to occur at an angle, making them longer and thus weaker than those in Anti-parallel beta-pleated sheets, where the inter strand hydrogen bonds are aligned directly opposite each other, resulting in stronger and more stable bonds. The angle formed by Parallel b-sheet is 135° & by Anti- parallel is 180°. The H-bond in Anti-Parallel are aligned directly opposite making it more stable. Thus it is preferred by nature more than Parallel b- sheet.