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Ashutosh posted an Question
October 14, 2020 • 00:59 am 30 points
  • IIT JAM
  • Biotechnology (BT)

You have purified some fab from igg myeloma protein. under appropriate conditions you could use this fab to generate antibodies against a. both kand à chain b.

You have purified some Fab from IgG myeloma protein. Under appropriate conditions you could use this Fab to generate antibodies against a. both Kand à chain b. y chain hinge region C. y chain allotypic determinants d. the idiotype of this myeloma [1ISC]

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    Narayan singh best-answer

    Ans is A. Antibodies typically consist of 2 heavy chains and 2 light chains. There are 5 kinds of heavy chains termed IgG, IgA, IgM, IgD, and IgE; and 2 distinct types of light chain, termed kappa and lambda. In myeloma, all the abnormal plasma cells make the same antibody.

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